Research groups
MTA-PTE Clinical Neuroscience MR Research Group
Tamás Dóczi (professor) E-mail:
Tel.: +36 72 536-000 (ext: 37695)
Research interest

The group has a general interest in non-invasively studying higher order human brain functions and in-vivo basic and applied research of endemic central nervous system disorders.

The lab is focused on

1, Human brain mapping of cognitive functions: language network and its lateralization; brain correlates of behavioral and psychological measures

2, Brain reward system: common biomarkers and pathomechanisms of different addictions (e.g. smoking, problematic internet use, obesity)

3, Traumatic brain injury: role of microbleeds; mechanisms of cerebrovascular functional disturbances; translation of results from animal studies to clinical practice

4, Parkinson’s disease (PD): early diagnosis; deep brain stimulation; neuroimaging based biomarkers of neurocognitive disorder in PD; neurostructural basis of anxiety in PD; brain functions of PD patients with good cognitive skills

5, Subcortical iron accumulation in healthy and diseased brains

6, Brain morphometric changes in migraine

7, Epilepsy research: identifying brain changes (focus) with advanced neuroimaging methods; association between hippocampal sclerosis, febrile seizure and temporal lobe epilepsy

Over the last 6 years we have built an arsenal of skills in scientific methods, including behavioral and psychological testing, statistics and different MR modalities that are useful for evaluating brain in-vivo. Our long term goal is to use advanced neuroimaging techniques to facilitate the better understanding of healthy brain and clinically relevant central nervous system disorders. The multidisciplinar nature of our staff (neuro physician, radiologist, informatics expert, biologist, physicist, radiographer, psychologist), advanced MR (1.5T and 3T) systems and wide range of MR compatible accessories significantly supports the research objectives of our group.

Clinical relevance

Using MRI for human brain mapping, our research group concentrates on understanding the normal functional anatomy of human brain and the brain correlates of human behavior, as well as those nervous system diseases, which are quite common in the modern society (addictions, traumatic brain injury, Parkinson’s disease, obesity), but their pathomechanisms are not entirely understood, and reliable biomarkers are missing. By identifying brain structures and changes underlying these conditions we may better understand their pathophysiology, anatomical background, clinical picture and therapeutical options.

Cambridge Research Systems - BOLDscreen 24 LCD for fMRI
Dedicated evaluation workstations for data processing
LCModel software
Magnetic resonance imaging systems
Maquet Servo-i MR compatible ventilator
MEDOC PATHWAY Pain & Sensory Evaluation System
Medrad Veris Cardiac MR general purpose MR compatible patient monitor
MEDRAD® Spectris Solaris EP Injection System
Multidetector CT scanner
NBS Presentation software
NordicNeurolab audio/video/response fMRI system
PACS DICOM archiving system
Magnetic Resonance Imaging (MRI)
Representative publications
A miniature optical neuronavigation system for CT-guided stereotaxy. von Jako C.R., Perlaki G., Orsi G., Schwarcz A., Doczi T.
Stereotactic and Functional Neurosurgery (2014/92(1): 1-7.)
DOI | PubMed | Scopus
Age at onset and seizure frequency affect white matter diffusion coefficient in patients with mesial temporal lobe epilepsy. Nagy S.A., Horvath R., Perlaki G., Orsi G., Barsi P., John F., Horvath A., Kovacs N., Bogner P., Abraham H., Bone B., Gyimesi C., Doczi T., Janszky J.
Epilepsy and Behavior (2016/61: 14-20.)
DOI | PubMed | Scopus
Comparison of accuracy between FSL's FIRST and Freesurfer for caudate nucleus and putamen segmentation. Perlaki G., Horvath R., Nagy S.A., Bogner P., Doczi T., Janszky J., Orsi G.
Scientific Reports (NATURE PUBLISHING GROUP) (2017/7(1): 2418.)
DOI | PubMed | Scopus
Differentiating white matter lesions in multiple sclerosis and migraine using monoexponential and biexponential diffusion measurements. Orsi G., Aradi M., Nagy S.A., Perlaki G., Trauninger A., Bogner P., Janszky J., Illes Z., Doczi T., Pfund Z., Schwarcz A.
Journal of Magnetic Resonance Imaging (2015/41(3): 676-683.)
DOI | PubMed | Scopus
Multi-modal magnetic resonance imaging in the acute and sub-acute phase of mild traumatic brain injury: can we see the difference? Toth A., Kovacs N., Perlaki G., Orsi G., Aradi M., Komaromy H., Ezer E., Bukovics P., Farkas O., Janszky J., Doczi T., Buki A., Schwarcz A.
Journal of Neurotrauma (2013/30(1): 2-10.)
DOI | PubMed | Scopus

Grants: Hungarian Brain Research Program 2.0 (2017-2021); Hungarian Scientific Research Fund (OTKA); EFOP 3.6.2-17-2017-00008 N (2017-2019);

Scholarships: Janos Bolyai Research Scholarship of the Hungarian Academy of Sciences; New National Excellence Program of the Ministry of Human Capacities (ÚNKP-17)